Abstract: Objective: To explore the effects of transcutaneous electrical acupoint stimulation(TEAS) on xerostomia in primary Sjögren's syndrome(pSS). Methods: A total of 80 patients with pSS admitted to the rheumatology and immunology department from July 2021 to June 2022 were selected,and divided into the control group(40 cases) and observation group(40 cases) according to the random number table method.The control group was given the usual care,while the observation group was treated with TEAS on Jiache points(ST6),Yifeng points(SJ17),Sanyinjiao points(SP6) and Zusanli points(ST36) based on usual care.The changes in the salivary flow rate,summated xerostomia inventory(SXI) score,medical outcomes study 36-item short form health survey(SF-36) score and nursing satisfaction in two groups were observed. Results: During the research,one patient dropped out from the control group,and 4 patients dropped out from the observation group.Eventually,a total of 75 patients were included,with 39 cases in the control group and 36 cases in the observation group.There was no statistical significance in the general data between two groups(P>0.05).After intervention,the salivary flow rate and all dimensions of SF-36 significantly increased,and the SXI score obviously decreased in two groups compared with those before intervention (P<0.05).Moreover,after intervention,the salivary flow rate,general health and energetic status of SF-36 in the observation group were higher than those in control group,the SXI score in the observation group was lower than that in ontrol group(P<0.05). Conclusions: TEAS can improve xerostomia in patients with Sjögren's syndrome,enhance their quality of life and improve their nursing satisfaction.