Abstract: Objective: To explore the relationship between myocardial bridging (MB) and mural coronary artery (MCA) atherosclerotic stenosis,and to identify risk factors associated with MCA stenosis. Methods: A retrospective analysis was conducted on 104 patients who underwent coronary CT angiography.Based on the presence of MB detected by coronary CT angiography,the patients were divided into MB group (n=43) and non-MB group (n=61).The degree of coronary artery stenosis was compared between the two groups.Logistic regression analysis was performed to identify the risk factors of MCA stenosis. Results: Among the coronary artery branches,MB was most frequently located in the left anterior descending branch,accounting for 55.81% (24/43) of cases.There was a statistically significant difference in the degree of coronary artery stenosis between the MB group and the non-MB group (P<0.05).MB thickness (OR=1.931,95%CI:1.066-3.497,P<0.05) and the tortuous degree of MB proximal vessel (OR=3.016,95%CI:1.232-7.387,P<0.05) were risk factors of MCA stenosis. Conclusions: MB is closely associated with MCA atherosclerotic stenosis.MB thickness and the tortuosity of the proximal vessel to the MB are significant risk factors influencing MCA stenosis.