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    慢性冠状动脉闭塞行介入治疗病人PNI与远期死亡率关系

    Relationship between PNI and long-term mortality in patients with chronic coronary artery occlusion undergoing interventional therapy

      摘要
    • 摘要:
      目的 探讨预后营养指数(PNI)与接受经皮冠状动脉介入治疗(PCI)的冠状动脉慢性完全闭塞(CTO)病人远期死亡率之间关系。
      方法 选取行PCI的CTO病人266例，根据PNI分为高PNI组(PNI≥48.5)134例和低PNI组(PNI < 48.5)132例；按照终点事件全因死亡，将病人分为存活组227例和死亡组39例。分析CTO行PCI病人远期死亡率的影响因素。
      结果 多因素回归分析显示，高龄和低PNI均为CTO病人全因死亡的独立危险因素(P < 0.05)。Kaplan-Meier生存分析显示，低PNI组病人远期MACE明显高于高PNI组(P < 0.05)(P < 0.05)。
      结论 入院时PNI是CTO行PCI病人远期死亡率的独立预测指标。

       

      Abstract:
      Objective To investigate the relationship between the prognostic nutritional index (PNI) and long-term mortality in patients with coronary chronic total occlusion (CTO) undergoing percutaneous coronary intervention (PCI).
      Methods A total of 266 CTO patients undergoing PCI were selected and divided into a high PNI group (PNI ≥48.5) (n=134) and a low PNI group (PNI<48.5) (n=132) based on PNI, and also divided into a survival group (n=227) and a death group (n=39) according to the endpoint event of all-cause death.The influencing factors of long-term mortality rate in patients undergoing PCI for CTO were analyzed.
      Results Multivariate regression analysis demonstrated that advanced age and low PNI were independent risk factors for all-cause mortality in CTO patients (P < 0.05).Kaplan-Meier survival analysis revealed that long-term MACE of patients in the low PNI group was significantly higher than that in the high PNI group (P < 0.05).
      Conclusions PNI at admission is an independent predictor of long-term mortality in CTO patients undergoing PCI.

       

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