Abstract: Objective: To study the ultrasonography and clinic-associated correlation factors of adverse pregnancy in patients with placenta previa,and build a prediction model. Methods: A retrospective study was conducted on 105 patients with placenta previa from January 2021 to September 2024.Based on the medical record system,the patients were divided into the occurrence group(n=33) and non-occurrence group(n=72) according to the adverse pregnancy outcome including the neonatal adverse outcomes(premature birth,asphyxia and low birth weight infants) and adverse maternal outcomes(such as postpartum hemorrhage and hysterectomy).The clinical relevant data of patients were collected and compared,and the logistic regression model was used to analyze the related factors of adverse pregnancy outcomes in patients with placenta previa.A clinical prediction model was constructed and presented visually through a nomogram.The predictive ability of nomogram model was evaluated through internal validation by drawing the receiver operating characteristic (ROC) curve,calibration curve and decision curve. Results: The differences in the history of miscarriage,parity,interval of second pregnancy <1 year,uterine lesions,scarred uterus and placenta accreta were statistically significant between two groups (P<0.05 to P<0.01).The results of logistic regression analysis revealed that all the above indicators were the risk factors affecting the occurrence of adverse pregnancy outcomes in patients with placenta previa(P<0.05 to P<0.01).Based on logistic analysis,a prediction model including the above five predictors was established,and the corresponding nomogram was drawn.The ROC curve was used to internally validate the model.The AUC value was 0.865(95%CI:0.768-0.962),the Brier Score was 0.107,and the P value of model fit was 0.002,with a statistic of 20.621,which indicated that this clinical prediction model had a relatively good risk prediction accuracy. Conclusions: The abortion history,birth time,second pregnancy interval<1 year,uterine lesions,scarred uterus and placenta implantation are all the independent influencing factors of adverse pregnancy outcomes in patients with placenta previa.Screening the high-risk groups by these indicators can provide the theoretical reference for scientific and effective clinical intervention measures during pregnancy.