蚌埠地区12所医院医院感染现患率调查及影响因素分析

    Prevalence and risk factors of nosocomial infection in 12 hospitals in Bengbu area

    • 摘要:
      目的: 了解蚌埠地区医院感染流行特征及影响因素,为制定有效的医院感染防控措施提供依据。
      方法: 采用床旁调查的方式,对蚌埠地区12家公立医院2021年12月24日00:00—24:00所有病人进行医院感染现患率调查。分析医院感染发生率、感染部位、感染病原菌、抗菌药使用情况及医院感染的影响因素。
      结果: 本研究共调查5 281名住院病人,医院感染现患率为1.14%,最常见的感染部位的呼吸系统(55.0%),医院感染发生率最高的科室是ICU(9.0%)。感染细菌中以大肠埃希菌和金黄色葡萄球菌居多(均占8.3%),本次调查中抗菌药物使用率为38.6%。多因素logistic回归分析结果显示,病人内在因素中极端年龄、实体肿瘤和昏迷是医院感染发生的独立危险因素(P < 0.05~P < 0.01),外部因素中动静脉插管、泌尿道插管、使用呼吸机、三类手术切口与医院感染的发生风险明显增加(P < 0.05~P < 0.01)。
      结论: 医院感染的主要影响因素有极端年龄、实体肿瘤、昏迷、动静脉插管、泌尿道插管、使用呼吸机和三类手术切口。识别医院感染风险因素,有助于识别高风险人群和高风险因素,可针对性地制定干预措施降低医院感染的发生风险。

       

      Abstract:
      Objective To understand the epidemiological characteristics and influencing factors of nosocomial infection in Bengbu area, and to provide basis for formulating effective prevention and control measures of nosocomial infection.
      Methods A bedside survey was conducted to investigate the prevalence of nosocomial infection among all patients in 12 public hospitals in Bengbu area from 0:00 to 24:00 on December 24, 2021. The incidence of nosocomial infection, infection site, infection pathogens, the use of antibiotics and the influencing factors of nosocomial infection were analyzed.
      Results A total of 5 281 hospitalized patients were investigated in this study. The prevalence rate of nosocomial infection was 1.14%, the most common infection site was the respiratory system (55.0%), and the department with the highest incidence of nosocomial infection was ICU (9.0%). Escherichia coli and Staphylococcus aureus accounted for 8.3% of the infected bacteria, and the use rate of antibiotics in this survey was 38.6%. Multivariate logistic regression analysis showed that extreme age, solid tumor and coma were the independent risk factors of nosocomial infection in the internal factors of patients (P < 0.05 to P < 0.01), while the external factors such as arteriovenous intubation, urinary tract intubation, ventilator use, class Ⅲ surgical incision and the risk of nosocomial infection were significantly increased (P < 0.05 to P < 0.01).
      Conclusions The main influencing factors of nosocomial infection are extreme age, solid tumor, coma, arteriovenous intubation, urinary tract intubation, use of ventilator and class Ⅲ surgical incision. Identifying risk factors of nosocomial infection is helpful to identify high-risk groups and factors, and formulate targeted interventions to reduce the risk of nosocomial infection.

       

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