Abstract: Objective: To investigate the proper operation method for colorectal carcinoma associated with acute intestinal obstruction.Methods: The clinical data of 48 patients with colorectal carcinoma associated with acute intestinal obstruction undergoing the surgical treatment from 1997 to 2006 were retrospectivedly analyzed.Twenty-four patients underwent colectomy with one-stage anastomosis,16 colectomy and the same pluged anastomotic stoma out of peritoneal cavity or Hartmann operation,8 double-cavity colostomy or by-pass.Results: Twenty-two patients experienced postoperative complications (45.8),including lung infection in 10 patients,wound infection in 8,peritoneal cavity infection in 2 and disruption of wound in 2.The perioperative mortality was 8.3 (4/48).Conclusions: Under the probable conditions,colectomy with one-stage anatomasis should be performed first.The active preoperative preparation and intensive postoperative treatment,the correct operation methods are important for reducing morbidity and mortality.