闭式引流及香菇多糖腔内灌注治疗恶性胸腹腔积液临床观察

Close drainage and intracavity perfusion of lentinan for treatment of malignant pleural-peritoneal effusion

摘要: 目的:观察闭式引流及香菇多糖灌注治疗恶性胸腹腔积液的疗效和毒副反应。方法:恶性胸腹腔积液住院患者80例,用一次性中心静脉导管行胸腹腔置管闭式引流胸腹腔积液,引流后腔内注入香菇多糖治疗。结果:80例患者中,完全缓解24例,部分缓解32例,总缓解率70.0%,无效+进展24例(30.0%)。结论:闭式引流及香菇多糖腔内灌注治疗恶性胸腹腔积液,疗效肯定且无明显不良反应。

Abstract: Objective: To observe the curative effect and side effect of close drainage and thoracic-abdominal cavity perfusion of lentinan in treating malignant pleural-peritoneal effusion.Methods: Eighty cases of malignant pleural-peritoneal effusion were performed splanchnocoele close drainage with central venous catheter and then perfused lentinan.Results: CR was observed in 24 cases,PR in 32 cases and NC+PD in 24 cases.Conclusions: The therapy of close drainage and intracavity perfusion of lentinan proves to be effective for treatment of malignant pleural-peritoneal effusion and has slight side effects.