Abstract: Objective: To summarize the experience of surgical therapy on Takayasu arteritis(TA),and investigate the timing of the surgical therapy and effective therapy methods on this disease.Methods: Eleven patients underwent surgical therapy,and 8 artery bypass operation,and 3 cases intervention therapy.The aim of therapy was to alleviate the severe symptoms of brain ischemia and refractory hypertension.The time of operation was appropriate.Results: Two patients died of brain oedema.The good curative effect was achieved in other patients.Follow-up in all the patients ranged from 6 months to 3 years.The symptoms were alleviated in all patients,and no recrudescence were found.The efficience was 63.6.Conclusions: On the condition that tackling operational time and adopting effective countermeasure,the good curative effect could be achieved in TA patients by surgical therapy.And safeguard of brain must be recognised in TA of Shimizi-sano.Intervention therapy still need incessant exploration and enhancement.