姜熙, 曹志刚, 罗勇, 陈其超. -硫辛酸治疗糖尿病神经源性膀胱39例[J]. 蚌埠医学院学报, 2014, 38(5): 583-584.
    引用本文: 姜熙, 曹志刚, 罗勇, 陈其超. -硫辛酸治疗糖尿病神经源性膀胱39例[J]. 蚌埠医学院学报, 2014, 38(5): 583-584.
    JIANG Xi, CAO Zhigang, LUO Yong, CHEN Qichao. Clinical effect of -lipoic acid in the treatment of diabetic neurogenic bladder:a report of 39 cases[J]. Journal of Bengbu Medical College, 2014, 38(5): 583-584.
    Citation: JIANG Xi, CAO Zhigang, LUO Yong, CHEN Qichao. Clinical effect of -lipoic acid in the treatment of diabetic neurogenic bladder:a report of 39 cases[J]. Journal of Bengbu Medical College, 2014, 38(5): 583-584.

    -硫辛酸治疗糖尿病神经源性膀胱39例

    Clinical effect of -lipoic acid in the treatment of diabetic neurogenic bladder:a report of 39 cases

    • 摘要: 目的:观察-硫辛酸治疗糖尿病神经源性膀胱(DNB)的临床疗效。方法:将39例DNB患者随机分为治疗组20例和对照组19例,2组均给予糖尿病基础治疗,其中治疗组还给予-硫辛酸治疗2周,对比治疗前后2组患者膀胱残余尿量差异。结果:治疗2周后,治疗组和对照组患者膀胱残余尿量均较治疗前均减少(P0.01和P0.05),且治疗组治疗后膀胱残余尿明显少于对照组(P0.01),治疗组有效率明显高于对照组(P=0.00)。结论:-硫辛酸治疗DNB效果显著,值得临床推广应用。

       

      Abstract: Objective:To investigate the effect of -lipoic acid on diabetic neurogenic bladder(DNB).Methods:Thirty-nine patients with DNB were randomly divided into treatment group(n=20) and control group(n=19).Both groups received the common therapy for diabetes,and the treatment group were administered -lipoic acid at the dose of for a 2-week course in addition.The changes of the patients' residual urine volume were compared between the two groups.Results:After 2 weeks of medication,the treatment group and the control group both showed a decreased residual urine volume as compared with that before the treatment(P0.01 and P0.05);the treatment group had a more obviously decreased residual urine volume than the control(P0.01).The total efficacy of the treatment group was significantly better than that of the control group(P=0.00).Conclusions:-lipoic acid can significantly decrease the residual urine volume in patients with DNB and is worthy to be popularized.

       

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