Abstract: Objective:To explore the processing method of general anesthesia in elderly patients.Methods:The clinical data of patients with 65 years old(including preoperative complications,cardiopulmonary functional status,results of auxiliary examination,anesthesia process and monitoring measures and postoperative complications) were retrospectively analyzed.Results:Twenty-three cases were treated with emergency surgical anesthesia,5 cases died.Serious ventricular arrhythmias in 2 cases were found.Postoperative acute myocardial ischemia in 3 cases were found,2 cases were successfully rescued and 1 case died.The delayed recovery in 3 cases,suspected cognitive dysfunction in 5 cases,cerebral infarction in 1 case,pulmonary embolism complicated with diabetes insipidus in 1 case and refractory hyponatremia in 1 case were found.Conclusions:The anesthesia maybe affect the heart,lung and brain functions of elderly patients with complex underlying diseases.Refinement,targeted,individualized general anesthesia management can improve the therapeutic intervention efficiency and recovery quality.