刘丽君, 杜丹丽. 卵巢浆液性癌54例临床分析[J]. 蚌埠医科大学学报, 2014, 38(5): 609-612.
    引用本文: 刘丽君, 杜丹丽. 卵巢浆液性癌54例临床分析[J]. 蚌埠医科大学学报, 2014, 38(5): 609-612.
    LIU Lijun, DU Danli. Clinical analysis of 54 cases of ovarian serous carcinoma[J]. Journal of Bengbu Medical University, 2014, 38(5): 609-612.
    Citation: LIU Lijun, DU Danli. Clinical analysis of 54 cases of ovarian serous carcinoma[J]. Journal of Bengbu Medical University, 2014, 38(5): 609-612.

    卵巢浆液性癌54例临床分析

    Clinical analysis of 54 cases of ovarian serous carcinoma

    • 摘要: 目的:探讨影响卵巢浆液性癌生存预后的因素。方法:具有完整病历资料的卵巢浆液性癌患者54例,记录患者的年龄、临床表现、临床分期、辅助检查。患者均行手术治疗,其中41例早期患者行分期手术,13例晚期患者行肿瘤细胞减灭术。术后均行辅助化疗,其中化疗疗程6次38例,<6次16例,并对临床资料进行分析。结果:患者发病年龄高峰在50~59岁17例,最常见的症状是腹痛(43例)、阴道出血(7例)、腹胀(35例)、扪及腹块(15例)。术中冷冻存在漏诊,而单一辅助检查难以确诊,需联合应用。术后化疗6 个疗程的患者生存率高于化疗<6 个疗程的患者(P0.05)。结论:卵巢癌筛查时应把肿瘤标志物的检测与症状、体征及影像学检查结合起来综合分析;提高术中冷冻的准确性尤为关键;肿瘤细胞减灭术,尽可能达到满意;术后尽量保证患者接受 6 次以上的化疗。

       

      Abstract: Objective:To investigate the factors affecting the survival prognosis of patients with ovarian serous carcinoma.Methods:Fifty-four patients with ovarian serous carcinoma were included in the study.The age,clinical manifestation,clinical stage and additional tests of the patients were analyzed.All the patients underwent surgical treatment.Forty-one early-stage cases were performed staging surgeries and 13 advanced cases cytoreductive surgeries.All of them received postoperative adjuvant chemotherapy.Thirty-eight cases received not less than 6 courses of chemotherapy and 16 cases less than 6 courses.Results:The peak age of onset was between 50 and 59,and the most common symptoms were abdominal pain(43 cases),vaginal bleeding(7 cases),abdominal distension(35 cases) and palpable abdominal mass(15 cases).Miss-diagnosis often occurred in intraoperative frozen and it was difficult to make a diagnosis by a single auxiliary examination,so combined examination was necessary.The survival rate of the patients having received not less than 6 courses of postoperative chemotherapy was high than that of patients having received less than 6 courses(P0.05).Conclusions:The screening of ovarian cancer should use a comprehensive analysis combining the detection of tumor markers,symptoms,physical signs and imaging;It is particularly important to improve the accuracy of intraoperative frozen;Effective cytoreductive surgery is essential;The patients should be assured to receive not less than 6 courses of postoperative chemotherapy.

       

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