动脉粥样硬化性脑梗死患者的血脂水平及颈动脉内膜中层厚度

Plasma lipids and carotid intima-media thickness in patients with atherosclerotic cerebral infarction

摘要: 目的:研究血脂水平及颈动脉内膜中层厚度(intima-mediathickness,IMT)与脑梗死的关系。方法:对103例动脉粥样硬化性脑梗死患者及52名正常对照组分别采血测定其血脂水平及颈动脉超声多普勒检查颈动脉IMT。结果:动脉粥样硬化性脑梗死组的血脂水平及IMT与对照组比较除高密度脂蛋白胆固醇(HDL-C)(P>0.05)外,其余指标均有统计学意义(P<0.05~P<0.01)。结论:血脂代谢异常是动脉粥样硬化性脑梗死患者的危险因素,动脉粥样硬化性脑梗死患者的颈动脉IMT较正常者增厚。

Abstract: Objective: To investigate the association between plasma lipid level and carotid intima-media thickness(IMT) in patients with atherosclerotic cerebral infarction.Methods: The plasma lipid level and carotid IMT in 103 cases of atherosclerotic cerebral infarction and 52 controls were measured.Results: There were significant differences between plasma lipid level and carotid IMT in the patients with atherosclerotic cerebral infarction and the control group(P<0.05-P<0.01),except the index of high-density lipoprotein cholesterol(P>0.05).Conclusions: Abmormal metabolism of plasma lipid level is a risk factor for patients with atherosclerotic cerebral infarction and their carotid IMT is thicker than that of the control group.