Abstract: Objective: To evaluate the clinical efficacy of retroperitoneal anatomical laparoscopy on adrenal tumorectomy. Methods: A total of six patients were operate on retroperitoneal anatomical laparoscopic adrenal tumorectomy. Results: Five cases were successful, one case converted to open surgery for excessive bleeding. The operation time was ranged from 60 min to 150 min. All patients recovered well with no obvious complications. Conclusions: Retroperitoneal anatomical laparoscopic adrenal tumorectomy has more advantages for clear operation field,less bleeding and complications. It could be a standard surgery option for adrenal tumor.