血清胆红素水平在冠心病诊断中的意义

Serum bilirubin concentration in diagnosis of coronary heart disease

摘要: 目的: 探讨血清胆红素水平变化对冠心病(coronary heart disease,CHD)诊断的意义。方法: 设冠心病组(CHD组)52例与对照组36例,测定血清总胆红素(TBIL)、总胆固醇(CHO)、甘油三酯(TG)、高密度脂蛋白(HDL)。结果: CHD组TBIL浓度明显低于对照组(P<0.01),CHD组TBIL浓度与CHO、TG均呈负相关关系(P<0.01),与HDL呈正相关关系(P<0.01)。结论: TBIL具有防止脂质氧化,从而可减少CHD的发生。

Abstract: Objective: To explore the value of serum bilirubin level in diagnosis of coronary heart disease(CHD).Methods: Fifty-two patients with CHD and thirty-six normal controls were divided into two groups.Total bilirubin(TBIL) in serum,total cholesterol(CHO),triglyceride(TG) and high-density lipoproteins (HDL) were measured.Results: The TBIL in serum in patients with CHD was lower than that in normal controls(P<0.01).The TBTL in CHD group showed negative correlativity with CHO and TG(P<0.01).The TBTL in CHD group showed positive correlativity with HDL(P<0.01).Conclusions: TBIL in serum could prevent lipid from oxidation and reduce the occurrence of CHD.