Abstract: Objective: To explore the characteristics,related factors and prognosis of poststroke depression(PSD).Methods: One hundred and ninety-two patients with cerebral stroke were investigated by sefl-rating depression scale(SDS) and Hamilton rating scall for depression(HAMD) about the occurrence of PSD and the clinical characteristics.Results: The occurrence rate of PSD was 37.5%.Among them,light deppression accounted for 20.8%,medium deppression 10.4% and heavy deppression 6.3%.The PSD was closely related to the damage situs and the degree of cerebral stroke.Conclusions: PSD is a familiar complication after cerebral stroke.It is closely related to the damage of nerve function and the patients' ability of daily living.Application of antidepressant agents in early treatment can improve the patients' life quality and recovery of nerve function.