高龄胃癌病人术后近期并发症的危险因素分析

    Analysis of the risk factors of recent postoperative complications in elderly patients with gastric cancer

    • 摘要:
      目的: 探讨高龄胃癌病人术后近期并发症发生的相关危险因素。
      方法: 回顾性选取80岁及以上行胃癌根治术病人93例作为研究对象。根据术后近期并发症情况进行分组;比较2组病人的术前、术中及术后资料。采用单因素分析和多因素logistic回归方法分析高龄胃癌病人术后近期并发症发生的危险因素。
      结果: 入组病人共发生术后近期并发症27例,占总数29.03%。单因素分析结果显示,术前体质量指数(BMI)、术前营养风险筛查2002(NRS2002)评分、是否合并糖尿病、是否合并慢性阻塞性肺疾病、是否联合脏器切除、术中出血量、手术时间与高龄胃癌病人术后近期并发症的发生具有相关性(P < 0.05~P < 0.01)。多因素logistic回归分析结果显示,术前BMI ≥ 25 kg/m2、术前NRS2002评分≥3分、合并慢性阻塞性肺疾病、术中出血量≥300 mL是术后近期并发症发生的独立危险因素(P < 0.05~P < 0.01)。
      结论: 术前BMI ≥ 25 kg/m2、术前NRS2002评分≥3分、合并慢性阻塞性肺疾病、术中出血量≥300 mL是高龄胃癌病人术后近期并发症发生的高危因素。

       

      Abstract:
      Objective To analyze the risk factors of recent postoperative complications in elderly patients with gastric cancer.
      Methods The clinical data of 93 patients aged 80 years undergoing radical gastrectomy were retrospectively analyzed. According to the recent postoperative complications, the patients were divided into observation group and control group. The preoperative data, intraoperative data and postoperative data between the two groups were compared. The univariate analysis and multivariate logistic regression were used to analyze the risk factors of recent postoperative complications in elderly patients.
      Results There were 27 cases of recent postoperative complications in all patients, accounting for 29.03% of the total. Univariate analysis results showed that preoperative body mass index (BMI), preoperative nutrition risk screening 2002 (NRS2002) score, whether combined with diabetes, whether combined chronic obstructive pulmonary disease, whether combined with organ resection, intraoperative bleeding volume, operation time were correlated with the occurrence of recent postoperative complications in elderly patients with gastric cancer (P < 0.05 to P < 0.01). Moreover, multivariate logistic analysis showed that preoperative BMI ≥ 25 kg/m2, preoperative NRS2002 score ≥ 3, the history of chronic obstructive pulmonary disease, intraoperative bleeding volume ≥ 300ml were the independent risk factors of recent postoperative complications (P < 0.05 to P < 0.01).
      Conclusion Preoperative BMI ≥ 25 kg/m2, preoperative NRS2002 score ≥3, the history of chronic obstructive pulmonary disease, intraoperative bleeding volume ≥300ml are the high-risk factors for the occurrence of recent postoperative complications in elderly patients with gastric cancer.

       

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