Abstract: Objective: To explore the relationship between occupational stress,coping style and social support and mental health in pediatric nurses.Methods: Two hundred and eighty pediatric nurses were investigated using the general demographic questionnaire,nurse job stressors scale,trait coping style questionnaire,social support rating scale and SCL-90 questionnaire by cross-sectional survey method.Results: The score of the nurse occupational stress was 76.11±13.19,the scores of the patient care and management and interpersonal dimension were high.The mean score of psychological health level of nurse was 71.54±42.42.Most pediatric nurse adopted positive coping style,the subjective support score was the highest in the nurse social support.The occupational stress,coping styles and useof social support of pediatric nurses were related to their mental health(P<0.05 to P<0.01).Conclusions: Pediatric nurse has the moderate occupational stress.Between occupational stress,social support and coping styles and mental health have a certain degree of correlation.