Abstract: Objective: To observe the adverse reactions of two kinds of external radiotherapy in cervical cancer,and provide the best therapeutic method.Methods: Sixty patients with stage B or worse cervical cancer were randomly divided into observation group and control group with 30 cases in each group,the observation group with the same center of external irradiation,5 times a week,every day and every wild tumor volume(DT) 1.0 Gy, daily exposure to two wild;the control group before and after wear on the field by pelvic irradiation in vitro, 5 times every week,every day and wild DT 1.8-2.0 Gy, daily two wild turns irradiation,pelvic external irradiation of DT 50 Gy,intracavitary brachy therapy for 3-7 times, once a week, each time DT for 6.0-7.0 Gy.The incidence of bone marrow suppression and digestive system reaction induced by radiotherapy were compared between the 2 groups.Results: The digestive system of reaction degree caused by radiotherapy group less than that in the control group(P< 0.05),the 2 groups had no significant differences in the degree of suppression of bone marrow(P>0.05). Conclusions: In cervical cancer,using in vitro irradiation with center can relatively reduce adverse reactions.