心力衰竭患者血浆尾加压素的变化
Plasma level of urotensin in heart failure patients
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摘要: 目的: 检测心力衰竭(心衰)患者血浆尾加压素(urotensinⅡ,UTN)的变化,探讨其在心衰中的临床意义。方法: 心衰组30例,NYHA心功能为Ⅱ~Ⅲ级;对照组19例,NYHA心功能分级Ⅰ级,采用放射免疫法测定血浆UTN.并作统计学分析。结果: 与对照组相比,UTN在治疗前心衰患者血浆中明显升高(P<0.01),并且不受年龄、性别、NYHA心功能分级和心脏疾病种类的影响(P>0.05)。结论: UTN是一个比较独立的危险因素,在心衰的诊断中有一定参考价值。Abstract: Objective: To investigate the change of plasma urotensin Ⅱ(UTN) levels in heart failure patients and its clinical significance.Methods: The UTN was measured in the plasma of 30 patients with heart failure(grade Ⅰ-Ⅲ by NYHA) and 19 controls(grade Ⅰ by NYHA),and the results were analyzed statistically.Results: The UTN was elevated in the plasma of heart failure patients(P<0.01) before treatment compared with that of the controls,and it was not related to the age,sex or heart function grade.Conclusions: Plasma UTN is a relatively independent risk factor,which is of use in the diagnosis of heart failure.
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