Abstract: Objective:To acquire better diagnosis and treatment by analyzing clinicopathologic features of non-menopausal and menopausal patients with cervical cancer. Methods:The clinical data of 100 cases with cervical cancer were analyzed retrospectively, and divided into non-menopausal group (32 cases) and menopausal group (68 cases) according to menopausal or not. Clinical presentation,tumor size,histological type,tumor stage and tumor metastasis of the two groups were studied and processed statistical analysis. Results:The contact bleeding symptoms in the non-menopausal group were more than that of the menopause group (P<0.01),2 groups of irregular vaginal bleeding symptoms was significantly(P<0.05). The size of tumor in the non-menopausal group was bigger than that of the menopausal group(P<0.05); and the proportion of non-squamous cell carcinoma was also more than the menopausal group(P<0.05). The cases of the non-menopausal group had early tumor stage,more ⅠandⅡperiod and less Ⅳ period amount compared with menopause group. However,the tumor metastasis cases in the non-menopausal group were more than menopause group(P<0.05). Conclusions:The non-menopausal patients with cervical cancer can lead easeily to contact bleeding,and accompany with large tumor volume and high proportion non-squamous cell carcinoma. The tumor is easy to transfer and has poor prognosis although its tumor stage is early in the non-menopausal patient.