Abstract: Objective: To evaluate the clinical efficacy of titanic elastic nailing fixation on long bone fractures in children after closed reduction.Methods: Sixty-seven children with long bone fractures were treated using titanic elastic nailing.Results: All the 67 cases were followed up from 3 to 18 months.No fracture redisplacement,nonunion or delayed union occurred.The average healing time was 6-8 weeks for the shaft of femur and tibiofibula,and 4-6 week for the humerus and shaft of radius.The internal fixation was removed 6 months later;the function of the affected limb and the neighboring joints were close to normal.Nail tail irritation and synovial sac formation occurred in 4 cases,which disappeared after removal of the implants.Conclusions: Titanic elastic nailing fixation is safe,effective and minimally invasive for treatment of children with long bone fracture with the advantages of faster healing and good functional recovery.The material deserves priority consideration for internal fixation.