Abstract: Objective: To observe the clinical effect of nursing intervention on the parturients in the labor with nuchal cord. Methods: One hundred and eighty parturients in labor with nuchal cord were divided into observation group and control group. The control group was given general nursing and necessary psychological intervention. The observation group used another temporary nursing before childbirth. Then outcomes of mother and infant were compared. Results: The rates of cesarean section and neonatal asphyxia in observation group were significantly lower than in control group (P < 0.01). Conclusions: The nursing intervention has a good clinical effect on the prognosis of mather and infant when the parturients in the labor with nuchal cord.