Abstract: Objective: To explore an effective procedure for management of hepatolithiasis.Methods: The clinical data of 43 patients with hepatolithiasis were analyzed retrospectively.All the cases were treated by regular hepatotomy combined with choledchoscope according to the stone location.Results: No improvement was observed in 2 cases.One of them occasionally had cholangitis,and the other had residual stones and recurrent cholangitis which needed reoperation.Conclusions: The procedure of regular hepatotomy combined with choledochoscope is safe and effective,and may significantly reduce the rate of residual stones.