Abstract: Objective: To explore the diagnostic value of CT in hemangiolymphangioma.Methods: The CT imaging and clinical data of 4 patients with hemangiolymphangioma diagnosed by pathology were retrospectively analyzed.Results: One case in left upper middle mediastinum and 3 cases in left side of retroperitoneum were found.All lesions were irregular multi-separated cystic mass,the size of which was about 9.1 cm×4.2 cm to 21.6 cm×8.1 cm.The lesions with multi-rooms were infiltrative growth along the tissue space.Some tiny linear or cable vascular enhancement imaging in cystic mass in arterial phase were found,which were obvious in venous phase,and accompanied different level enhancement in septum.Conclusions: CT has important value in the diagnosis of hemangiolymphangioma.