Abstract: Objective: To explore the risk factors and effectiveness of secondary prevention on stroke to patient's recovery,life quality,treatment compliance.Methods: One hundred and eighty patients with stroke were divided into observation group(n=90) and control group(n=90) randomly.Health records were set up and self designed scale for assessment of risk factors of recurrence of stroke was used to assess the patient's general conditions.Individual intensified education and behavior intervention were carried out based on the evaluation in observation group;while routine therapy and essential health education were given to patients in control group.The general evaluation of the collected data was made after 3 months and 6 months.Results: In the observation group,the exactitude of mastering knowledge of diseases and correction of non-health habit and compliance were evidently higher than that in control group(P<0.01);and the rate of recurrence of stroke was lower than that in control group(P<0.05 and P<0.01).Conclusions: Secondary prevention can effectively reduce the recurrence of stroke and improve the quality of patient's life.