Abstract: Objective: To explore the diagnosis and surgical treatment of pulmonary sequestration.Methods: The clinical data of 10 cases of pulmonary sequestration were retrospectively studied.Results: The preoperative misdiagnosis was 100% and all the 10 cases were identified by exploration in operation.No hemorrhage or other complications occurred and all the cases were discharged after full recovery.Conclusions: Cognition to pulmonary sequestration should be elevated.The exploration operation shows that the features of pulmonary sequestration are adhesion and clausura of pectus,pink lung tissues with no locus niger and abnormal impulse of vasa which can be touched near the ligament of lower lobe.Correct diagnosis is key to the treatment of pulmonary sequestration.