Abstract: Objective: To study the clinical application value and nursing point of transfusion pump in chemotherapy for multiple myeloma. Methods: Twenty-three patients with multiple myeloma were final diagnosis, 11 patients were distributed into treatment group and others were control group randomly. Infusion pump was adopted in treatment group, while common transfusion was used to control group. All treatment projects were VAD. Results: Twenty-six and 29 courses of chemotherapy were undertaken in treatment group and control group respectively. The incidence rates of phlebophlogosis, skin destruction, nausea and vomiting, dental ulcer and costiveness in treatment group were lower than those in control group, the difference were significance (P<0.05-P<0.01). Conclusions: The method of administer drags has the characteristics of persistent rate and quanitity, dose stability in unit time and adver-se reaction little, it is good method for its safety credibility, simpleness efficianey and time-saving.