Abstract: Objective: To discuss the clinical significance of changes of blood sodium,potassium,calcium and glucose in children with febrile convulsion(FC).Methods: Thirty-two cases of hospitalized FC patients were concluded in FC group,30 cases of upper respiratory infection with fever symptoms were concluded in fever group and 30 cases of healthy children acted as controls.The blood sodium,potassium calcium and glucose level were determined and analyzed among the three groups.Results: The blood potassium and calcium had no significant difference between FC group and fever group;the blood sodium and glucose had no significant difference between fever group and the controls(P>0.05);the blood sodium in FC group was significantly lower than that in the fever group and the normal controls,while the blood glucose was higher than that of the latter two groups(P<0.01).Conclusions: There is close relation between low blood sodium and FC;low blood sodium is the consequence of FC,and may lower the convulsion threshold;low blood calcium may be the result of fever and FC,and may also be the inducing factor;the blood glucose level of FC patients may have a transient rise.