Abstract: Objective: To investigate the clinical efficacy of loop electrosurgical excision procedure(LEEP) in treatment of cervical lesions.Methods: Thirty-one patients with different cervical diseases were diagnosed by optical observation,cytology,colposcopy and cervical biopsy.The lesions were treated with LEEP.The cure rate,the operative time,bleeding volume and postoperative effects were recorded.Results: The cure rate of LEEP was 96.78%.The mean operative time was 4.65 minutes.The mean bleeding volume was 4.97 ml.No secondary bleeding and postoperative infection occurred.All these surgical specimens were examined and the diagnosis was confirmed by pathology.Conclusions: The LEEP in management of the cervical diseases is simple and safe with short operative time,less bleeding and vaginal discharge.It is the best method in treatment of cervical pathological lesions.