前列腺增生经尿道电汽化术后药物镇痛效果比较

    Comparison of different analgesia effects for patients undergoing transurethral electrovaporization of the prostate

    • 摘要: 目的: 比较不同药物用于前列腺电汽化术后镇痛的效果和副反应。方法: 80例患者分为4组,布比卡因组(Ⅰ组)用0.125%布比卡因;曲马多组(Ⅱ组)用10 g/L曲马多,吗啡组(Ⅲ组)用0.1 g/L吗啡,芬太尼组(Ⅳ组)用0.005 g/L芬太尼。负荷量均为2 ml,背景剂量均为2 ml/h。术后分别观察视觉模拟评分(VAS)、镇静评分以及血压、心率、呼吸频率、血氧饱和度和恶心呕吐等副反应情况。结果: VAS评分Ⅱ组、Ⅲ组、Ⅳ组近似,Ⅰ组高于其他3组(P<0.01),Ⅱ组镇静评分高于Ⅰ组(P<0.05),其他3组近似(P>0.05);Ⅱ组心率高于其他3组(P<0.01);呼吸频率Ⅰ和Ⅱ组均高于Ⅲ和Ⅳ组(P<0.05~P<0.01)。结论: 各组病例镇痛效果满意,曲马多、吗啡、芬太尼相对优于布比卡因。

       

      Abstract: Objective: To compare the clinical effects and adverse effects of different analgesias on patients receiving transurethral electrovaporization of the prostate.Methods: Eighty adult patients were divided into four groups.Group Ⅰ were administered (0.125%) bupivacaine,group Ⅱ 10 g/L tramadol,group Ⅲ 0.1 g/L morphine and group Ⅳ 0.005 g/L featanyl.The visual analog scale(VAS),analgesia doses,BP,HR,RR,SpO2 and the adverse effects in forms of nausea and vomiting were observed.Results: The VAS of group Ⅰ was the highest among the four groups(P<0.01).The tranquilizing score of group Ⅱ was somewhat higher than that of group Ⅰ (P<0.05),while it was similar in other three groups (P>0.05).The incidence of HR in group Ⅰ was higher than that of the other three groups(P<0.01) and the incidence of RR was different between each other in all the four groups(P<0.01).Conclusions: The analgesia effect in each group is satisfactory,but the effect of group Ⅱ,Ⅲ and Ⅳ is somewhat better than that of group Ⅰ.

       

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