Abstract: Objective: To probe into the gastroscopic and clinical characteristics of the peptic ulcer in the students of the middle and primary school.Methods: Thirty-five cases of the peptic ulcer in the students of the middle and primary school confirmed by gastroscope in past 8 years were analyzed retrospectively.Results: Among the 35 patients,27 were middle school students and 8 were primary school students.The ratio of middle school students and primary school students was 3.4:1;and the ratio of male and femal was 2.9:1;26 were of duodenal ulcer(74.3%),7 gastric ulcer(20.0%) and 2 compounding ulcer(5.7%); Helicobateria pylori infection rate was 54.3%.Conclusions: As the clinical symptoms of peptic ulcer in students of middle and primary schools are not typical,it is liable to misdiagnosis,or leak diagnosis,delaying the treatment in time.Gastroscopy is an easy,safe and reliable method for the diagnosis of the disease.