Abstract: Objective: To investigate the levels of uric acid in type 2 diabetic patients with cerebral infarction,and its clinical significance.Methods: The levels of fasting serum uric acid concentrations,blood glucose,glycosylated hemoglobin and lipid in simple diabetes group,cerebral infarction without diabetes group,type 2 diabetes complicated with cerebral infarction and normal control group(60 cases each group) were detected and analyzed using automatic biochemical analyzer.Results: The levels of uric acid in type 2 diabetic patients with cerebral infarction were significantly higher than those in other three groups(P< 0.01),the levels of uric acid in simple diabetes group and cerebral infarction without diabetes group were significantly higher than those in control group(P< 0.01).Conclusions: High uric acid level may be an independent risk factor of the type 2 diabetic patients with cerebral infarction.