Abstract: Objective:To evaluate the relationship between the levels of lipoprotein,apoprotein(Apo),ApoB/ApoA-Ⅰ ratio,and LP (a) and coronary heartdisease(CHD). Methods:Sixty-one patients diagnosed as CHD were as the CHD group,20 healthy people were selected as control. The levels of TG,TC,HDL-C,LDL-C,ApoB,ApoA-Ⅰ,and LP(a) were detected. Results:There were significantly differences between the group CHD and control in the levels of HDL-C,ApoB,LP(a),and ApoB/ApoA-Ⅰratio(P<0.05). Among lipid index,HDL-C,ApoB and LP(a) were the independent risk factors for CHD by using of Logistics stepwise regression analysis. Correlation analysis found that ApoB,Lp(a) and ApoB/ApoA-Ⅰ ratio were positive correlation with CHD. There were no significant correlations for other results. Conclusions:There are more valuable to predict the risk factor when associated with ApoB,ApoB/ApoA-Ⅰ ratio and Lp(a).