刘先富, 郭伟, 刘道永. 低龄青年乳腺癌与中老年乳腺癌患者临床及病理特征比较[J]. 蚌埠医学院学报, 2014, 39(11): 1491-1494.
    引用本文: 刘先富, 郭伟, 刘道永. 低龄青年乳腺癌与中老年乳腺癌患者临床及病理特征比较[J]. 蚌埠医学院学报, 2014, 39(11): 1491-1494.
    LIU Xian-fu, GUO Wei, LIU Dao-yong. Comparison of the clinical and pathological features of breast cancer between young and elderly patients[J]. Journal of Bengbu Medical College, 2014, 39(11): 1491-1494.
    Citation: LIU Xian-fu, GUO Wei, LIU Dao-yong. Comparison of the clinical and pathological features of breast cancer between young and elderly patients[J]. Journal of Bengbu Medical College, 2014, 39(11): 1491-1494.

    低龄青年乳腺癌与中老年乳腺癌患者临床及病理特征比较

    Comparison of the clinical and pathological features of breast cancer between young and elderly patients

    • 摘要: 目的:比较低龄青年乳腺癌与中老年乳腺癌患者的临床病理特征、分子分型及预后情况。方法:收集18~30岁低龄青年乳腺癌56例(低龄青年组)和同期45~70岁中老年乳腺癌120例(中老年组)。比较2组的临床病理特征、分子分型及预后。结果:2组在肿瘤大小、淋巴结转移、组织学分级、分子分型及肿瘤复发方面差异均有统计学意义(P<0.05~P<0.01),低龄青年组更易出现三阴乳腺癌。结论:低龄青年乳腺癌临床症状隐蔽,预后不佳,与中老年乳腺癌有不同的临床病理特征、分子分型及预后,应重视早期诊断与治疗。

       

      Abstract: Objective: To compare the clinical and pathological features,molecular subtypes and prognosis of breast cancer between young and elderly patients.Methods: Fifty-six young patients with breast cancer,18 to 30 years old,and 120 elderly patients with breast cancer,45 to 70 years old,were divided into the young group and elderly group,respectively.The clinical and pathological features,molecular subtypes and prognosis between two groups were compared.Results: The differences of the tumor size,lymph node metastasis,histological grade,molecular subtype and tumor recurrence between two groups were statistically significant(P<0.05 to P<0.01).The triple negative breast cancer occurred most often in young group.Conclusions: The clinical symptom of breast cancer in young patient is concealment,and its prognosis is poor.The clinical and pathological features,subtypes and prognosis of breast cancer in young patients are different from that in the elderly patients,the early diagnosis and treatment of which should be paid attention to.

       

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