Objective To systematically quantify the morphological characteristics of the nasolabial groove using the Cartesian coordinate system, establish the corresponding regression model and construct a simulated linear fitting relationship.

Methods Based on the coordinate values reading of the lateral margin of the inferior frontal sulcus in 40 healthy adults' brains, a data set was constructed. The Cartesian coordinate parameter values of the inferior frontal sulcus were extracted using image reading software. The projection scatter plot of the lateral margin of the inferior frontal sulcus was drawn using its chart function, and the regression model and simulated linear fitting relationship of the lateral margin of the inferior frontal sulcus were analyzed using SPSS 23.0 software, and its correlation coefficient was analyzed.

Results The lateral edge of the inferior frontal sulcus was mainly distributed in the area 6 to 28 mm above the anterior and posterior junction planes. The difference in the vertical direction of the inferior frontal sulcus on both sides of the same gender was not significant. In men, the left inferior frontal sulcus was more widely dispersed in the left and right directions than in the right direction, while in women, the left inferior frontal sulcus is more widely dispersed in the front and back directions than in the right direction. The regression lines of the inferior frontal sulcus on different surfaces in men did not have a linear relationship, while in women, there was a linear relationship in the right inferior frontal sulcus. The variation regularity of the bilateral inferior frontal sulcus was strong in men, while in women, the variation of the left inferior frontal sulcus was greater and that of the right one was relatively stable. The left inferior frontal sulcus in women had a greater degree of variation than the right one, which is related to the curvature of the left inferior frontal sulcus in the left-right and up-down directions of human body.

Conclusions Establishing a regression model for the inferior frontal sulcus and simulating the linear fitting relationship provides important anatomical basis for personalized medicine and minimally invasive surgery.