Abstract: Objective: To study the relationship between cerebrovascular accident complication and plasma high-sensitivity C-reactive protein(Hs-CRP) level in patients with chronic renal failure.Methods: Twenty-eight cases of chronic renal failure with cerebrovascular accident complication(groupA) and 32 cases without cerebrovascular accident complication(group B)were detected of the levels of plasma Hs-CRP,age,plasma triglyceride(TG),total cholesterol(CHO),high-density lipoprotein cholesterol(HDL),serum creatinine(Scr),plasma albumin(ALB)and blood urea nitrogen(BUN).The results were compared with those of 30 healthy ontrols(group C).Results: The level of plasma Hs-CRP in group A and group B was significantly increased compaired with that of group C(P<0.01).The level of plasma Hs-CPR in group A was significantly increased compared with that of group B and the difference was great(P<0.01).The level of Hs-CRP was apparently affected by plasma triglycericle TG,CHO,HDL,Scr,ALB and BUN,but had no relations with age(P>0.05).Conclusions: The Hs-CRP level is high in patients with chronic renal failure accompanied by cerebrovascular accident complication.Observation of Hs-CRP level is essential to predict the occurrence of cerebrovascular accident complicatio in patients with chronic renal failure.