Abstract: Objective: To observe the curative effect of aciclovir on ocular herpes zoster.Methods: Aciclocir 0.5 g in 0.9% sodium chloride solution 250 ml were administered intravenously twice a day for 8 hours.Results: All 35 patients were cured.The course of disease was shortened by more than a half.The patients aged less than 35 years old were cured in 5 or 6 days,those aged between 36 and 49 years were cured in 5 to 8 days,those aged between 50 and 74 years were cured in 8 or 9 days,and those with complications were cured in 1 week to 2 weeks.Conclusions: The mechanism of aciclovir on ocular herpes zoster is to compete receptor with virus.Extending the transfusion time can extend the time to compete receptor with virus.Thus,transfusion must be maintained long enough to increase the curative effect.