Abstract: Objective: To investigate the effects of absorbable hemostat(TiSTAT) in transoral endoscopic adenoidectomy.Methods: Eighty adenoid hypertrophy patients treated with transoral endoscopic adenoidectomy were randomly divided into group A(use TiSTAT) and group B(no-use TiSTAT).The intraoperative blood loss,operative time,surgical complications,postoperative recovery and curative effects between two groups were compared.Results: The intraoperative blood loss,operative time and the rate of postoperative rebleeding in group A were significantly less than those in group B(P<0.01).The differences of postoperative recovery and curative effects between two groups were not statistically significant(P>0.05).Conclusions: The application of absorbable hemostat in transoral endoscopic adenoidectomy through mouth is safe and effective,which can decrease blood loss,shorten operative time and reduce postoperative rebleeding and complications.