Abstract: Objective: To evaluate the clinical efficacy of three different operative patterns of hysterectomy including laparoscopic hysterectomy(LH),trans-abdominal hysterectomy(TAH) and trans-vaginal hysterectomy(TVH).Methods: A retrospective analysis on 404 patients undergoing hysterectomy was carried out including the operating time,the bleed volume,the complications and the postoperative recovery.Results: The operating time,the bleed volume and hospitalized time in TAH group were longer and greater than those in LH group and TVH group(P<0.01).The operating time was also longer in LH group than in TVH group(P<0.01).It could be found that there was significant difference in surgical complications among the three groups(P<0.05).All patients recovered well postoperatively.Conclusions: The three operative patterns are ideal for hysterectomy.Optimal choice for patients to undergo hysterectomy should depend on idiographic clinic circumstance such as patient condition and preference,the gynaecological surgeon's skills and so on.