冠状动脉硬化患者血清超敏C反应蛋白及胆红素检测的临床意义

    Determination of levels of h-CRP,DBil and TBil in serum and analysis of correlation between their levels and arteriosclerosis

    • 摘要: 目的: 探讨冠状动脉粥样硬化患者血清中超敏C反应蛋白(h-CRP)及总胆红素(TBil)、直接胆红素(DBil)含量与冠状动脉粥样硬化患者间的关系。方法: 采用乳胶增强免疫比浊法和速率法,分别检测48例冠状动脉粥样硬化患者和50名健康人血清的h-CRP和TBil、DBil。结果: 冠状动脉粥样硬化患者的h-CRP含量显著高于健康人(P<0.001),而TBil、DBil均显著低于健康人(P<0.001)。结论: 检测血清h-CRP、TBil、DBil含量,有助于动态观察及评估冠状动脉粥样硬化的发生风险,防止冠心病的发生。

       

      Abstract: Objective: To investigate the serum levels of high sensitivity C reactive protein (h-CRP), total bilirubin (TBil) and direct bilirubin (DBil) in patients with coronary arteriosclerosis and the correlation between their levels and arteriosclerosis. Methods: The levels of h-CRP was determined by latex-enhanced immunoturbidimetric, DBil and TBil were determined by continuous monitoring assay in 48 patients with coronary arteriosclerosis and 50 controls. Results: Compared with the control, the levels of h-CRP, DBil and TBil in these patients had statistically significant differences. The levels of h-CRP of these patients were higher than those of the control (P<0.001) while the levels of DBil and TBil were lower (P<0.001). Conclusions: The determination of the levels of hs-CRP, DBil and TBil in serum can help in evaluating the severity and the risk of coronary arteriosclerosis, which will prevent coronary artery disease.

       

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