老年慢性心功能不全病人死亡焦虑与短期预后因素分析

    Analysis of death anxiety and short-term prognostic factors in elderly patients with chronic cardiac insufficiency

    • 摘要:
      目的: 探讨老年慢性心功能不全(ECCI)病人死亡焦虑与短期预后的影响因素。
      方法: 选取79例ECCI病人作为研究对象,采用基本资料调查表、死亡焦虑量表(T-DAS)、家庭关怀度指数问卷(APGAR)进行调查,收集临床相关资料并评估短期预后,分析ECCI病人死亡焦虑及短期预后的影响因素。
      结果: 79例ECCI病人死亡焦虑发生率为40.51%(32/79)。单因素分析和logistic回归分析显示,失眠是ECCI病人死亡焦虑的独立危险因素(P < 0.05),个人月收入高是死亡焦虑的保护因素(P < 0.05)。在短期预后方面,预后不良组与预后良好组N末端B型利钠肽原(NT-proBNP)、血栓素B2(TXB2)差异均有统计学意义(P < 0.05)。ROC曲线分析显示,NT-proBNP、TXB2单独预测ECCI病人短期预后不良的AUC分别为0.747、0.898(P < 0.05)。
      结论: ECCI病人死亡焦虑发生率较高,个人月收入低、失眠是其独立影响因素,NT-proBNP、TXB2对短期预后有一定预测价值。

       

      Abstract:
      Objective To explore the influencing factors of death anxiety and short-term prognosis in elderly patients with chronic cardiac insufficiency (ECCI).
      Methods Seventy-nine patients with ECCI were selected as the study subjects, and were investigated by using the Basic Information Questionnaire, Death Anxiety Scale (T-DAS) assessment, and Family Caring Degree Index Questionnaire (APGAR) to collect clinically relevant information and assess short-term prognosis. The influencing factors of death anxiety and short-term prognosis of ECCI patients were analyzed by univariate analysis and binary logistic regression.
      Results The incidence of death anxiety in 79 ECCI patients was 40.51% (32/79). Univariate and logistic regression analyses yielded that insomnia was an independent risk factor for death anxiety (P < 0.05), and high personal monthly income was a protective factor for death anxiety (P < 0.05). In terms of short-term prognosis, the differences in N-terminal B-type natriuretic peptide proteins (NT-proBNP) and thromboxane B2 (TXB2) were significant when comparing the poor prognosis group with the good prognosis group (P < 0.05); The area under the curve (AUC) for ROC curve analysis of NT-proBNP and TXB2 were 0.7467 and 0.8984, respectively (P < 0.05).
      Conclusions The high incidence of death anxiety in ECCI patients is associated with low personal monthly income and insomnia, and NT-proBNP and TXB2 have a predictive value for short-term prognosis.

       

    /

    返回文章
    返回