Abstract: Objective: To investigate the recurrence rate of gallstone complicated with common bile duct stones treated with laparoscopic cholecystectomy(LC) combined with T tube drainage(LCHTD),and its influencing factors.Methods: The clinical data of 319 gallstone complicated with common bile duct stones patients treated with LC combined with LCHTD were retrospectively analyzed.The recurrence rate of gallbladder stone after 1 to 5 years of operation was observed,and the risk factor of which was investigated.Results: The recurrence rates after 1,3 and 5 years of operation were 4.39%(14 cases),9.40%(30 cases)and 14.73% (47 cases),respectively.The results of non-conditional logistic regression analysis showed that the multiple stones,lithotripsy,common bile duct dilatation and gallbladder tube dilatation were the independent risk factors of postoperative recurrence of cholecystolithiasis after LC combined with LCHTD treatment(OR=1.721,1.582,1.404 and 1.381,respectively,P<0.05).Conclusions: The lithotripsy,multiple stone,dilatation of common bile duct and dilation of gallbladder tube are the independent risk factors of recurrence of cholecystolithiasis after LC combined with LCHTD treatment.