Abstract: Objective: To explore the effects of the nursing intervention on improving the postoperative pain in patients with ENT(ear,nose and throat)surgery.Methods: Fifty patients treated with ENT surgery were set as the observation group,and nursed with comprehensive nursing intervention.Fifty patients treated with ENT surgery from March 2011 to August 2012 were set as the control group,and nursed with the conventional nursing method.The visual analogue scale score at postoperative 24 h and 72 h,and analgesic usage rate,pain level proportion and total efficacy at postoperative 72 h in two groups were observed.Results: The visual analogue scale score at postoperative 24 h and 72 h and analgesic usage rate at postoperative 72 h in observation group were significantly lower than those in control group(P<0.01).The total rate of pain in observation group and control group were 12.0% and 68.0%,respectively,the difference of which was statistically significant(P<0.01).The totally effective rate in observation group and control group were 100.0% and 90.0%,respectively,the difference of which was statistically significant(P<0.01).Conclusions: Comprehensive nursing intervention can effectively improve the postoperative pain,and promote the postoperative recovery of patients,which is worthy of popularizing.