Abstract: Objective:To study the distribution of peroneal artery of lateral post-clearance and vascular diameter and hemodynamic parameters by high-resolution color Doppler flow imaging(CDFI) provides a basis of the preoperative evaluation of vascular quality and the design of low-rotation point sural neurovascular flap. Methods:A total of 9 cases patients were collected for this study from December 2009 to March 2011,each case was detected the number of perforating branches of the peroneal artery,the beginning of diameter and hemodynamic parameters which the initial diameter is bigger than 0.5 mm and the range is 0 to 3 cm from the lateral tip, then mark the location of where it pierces the deep fascia and implement the operation of low-rotation point sural neurovascular flap graft. Results:Twenty-two perforating arteries were recorded,initial diameter of perforating arteries were (0.78±0.23) mm,the length of the piercing point from deep fascia to the lateral tip was(1.66±0.91) cm,the vascular flow peak systolic velocity was (0.19±0.03) m/s. The location of the perforating point from deep fascia and traveling direction were completly anastomosised with preoperative positioning of the body surface. All flaps survived completely. Conclusions:CDFI can show the distribution of peroneal artery of lateral post gap and vascular diameter and hemodynamic condition and can accurately locate the surface positioning,which can be used for preoperative evaluation of the quality of perforating branches of blood vessels and provide scientific basis for the design of low-rotation point of sural neurovascular flap.