蒋斌. 大学新生HBsAg及丙氨酸氨基转移酶检测分析[J]. 蚌埠医学院学报, 2010, 35(8): 826-827.
    引用本文: 蒋斌. 大学新生HBsAg及丙氨酸氨基转移酶检测分析[J]. 蚌埠医学院学报, 2010, 35(8): 826-827.
    JIANG Bin. Investigation of HBsAg and alanine aminotransferase among new students of college[J]. Journal of Bengbu Medical College, 2010, 35(8): 826-827.
    Citation: JIANG Bin. Investigation of HBsAg and alanine aminotransferase among new students of college[J]. Journal of Bengbu Medical College, 2010, 35(8): 826-827.

    大学新生HBsAg及丙氨酸氨基转移酶检测分析

    Investigation of HBsAg and alanine aminotransferase among new students of college

    • 摘要: 目的:了解大学新生乙型肝炎(乙肝)病毒感染及肝功能情况,为在校大学生乙肝的预防提供依据。方法:对2006、2007、2008级6953名入学新生采用ELISA检测HBsAg;采用动力学方法测定血清丙氨酸氨基转移酶(ALT)。结果:2006、2007、2008级新生HBsAg阳性率分别是3.19%、3.38%、2.07%,总阳性率为2.87%,较2006年全国人群乙肝血清流行病学调查的HBsAg阳性率8.57%低;2006、2007、2008新生HBsAg阳性率差异有统计学意义(P<0.05);男、女生总检出HBsAg阳性率差异有统计学意义(P<0.01),各年级男、女生间HBsAg阳性率差异也有统计学意义(P<0.01);各年级新生ALT异常率差异均无统计学意义(P>0.05)。结论:大学新生HBsAg阳性率较低,男生阳性率明显高于女生,ALT异常率较低;学校要继续加强乙肝的健康教育,增加体检检验项目,对易感者进行乙肝疫苗接种。

       

      Abstract: Objective: To know about the situation of hepatitis B virus infection and the liver function among college freshman,in order to provide the scientific basis for prevention and education work.Methods: Firstly used enzyme linked immunosorbent assay to check HBsAg carriers of freshmen 2006,2007,2008;then used kinetic method to determine the serum alanine aminotransferase (ALT).Results: The positive rates of HBsAg were 3.19%,3.38%,and 2.07% among freshmen 2006,2007,and 2008,respectively;and 2.87% among the total students.The positive rate was significantly lower than the level of national population seroepidemiological survey of hepatitis B (8.57%) in 2006.The difference of positive rates was statistically significant among freshmen 2006,2007,and 2008 (P < 0.05).The difference of positive rates was statistically significant between male students and female students (P<0.01).And the difference of positive rates was also statistically significant between male students and female students among freshmen 2006,2007,and 2008,respectively (P<0.01).The difference of abnormity rate about ALT was not statistically significant among freshmen 2006,2007,and 2008 (P>0.05).Conclusions: The positive rate of HBsAg is low among freshmen.The positive rate of male students is significantly higher than that of female students.The abnormity rate of ALT is low.The college must strengthen health education of the hepatitis B to the students,increase physical examination items and have them vaccinated against hepatitis B virus.

       

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