布地奈德联合沙丁胺醇雾化吸入治疗慢性阻塞性肺疾病加重期53例疗效分析

Budesonide and salbutamol inhation therapy for chronic obstructive pulmonary disease

摘要: 目的:观察雾化吸入布地奈德、沙丁胺醇治疗慢性阻塞性肺疾病急性加重期(AECOPD)的效果。方法:106例AECOPD住院患者,随机分2组,对照组53例给予常规治疗,治疗组53例给予常规治疗的同时,吸入布地奈德、沙丁胺醇混悬液。分析治疗后患者临床呼吸困难症状改善、肺部罗音的吸收和住院天数的变化。结果:治疗组呼吸困难症状明显改善,肺部罗音明显吸收,住院天数明显缩短,与对照组差异均有统计学意义(P<0.05~P<0.01)。结论:布地奈德联合沙丁胺醇雾化吸入对AECOPD疗效肯定,并且副作用小,可作为治疗AECOPD的有效方案。

Abstract: Objective: To investigate the effects of budesonide and salbutamol on patients with chronic obstructive pulmonary disease(COPD).Methods: One hundred and six patients with COPD were randomly divided into two groups.The control group received routine therapy only,while the treatment group were administered inhalation of budesonide and salbutamol in addition to the routine therapy,then the outcome was analyzed.Results: Compared with the control group,the treatment group manifested a significant improvement in dyspnea,bellows rales and time of hospital stay(P<0.05-P<0.01).Conclusions: Inhalation of budesonide and salbutamol therapy has an affirmative effectiveness on COPD with little side effect.