Abstract: Objective: To explore the improving approaches of medical college students' humanistic quality at a cross-cultural perspective.Methods: Several specific approaches were put forward to enhance medical college students' humanistic quality by analyzing the internal relations between cross-culture and medical college students' humanistic quality.Results: Under a cross-cultural horizon,multiple channels could be adopted to improve medical college students' humanistic quality,including strengthening humanism ideological education of the Chinese tradition medicine culture,enhancing students' humanistic quality via college English class,improving teachers' humanistic quality,offering some related selective courses and constructing campus culture,these approaches were very effective.Conclusions: It is very significant to carry out medical humanistic quality education to make medical college students improve their abilities to identify and choose western culture.