Abstract: Objective: To evaluate the function of the echocardiogram in percutaneous closure of ventricular septal defects(VSD).Methods: The echocardiography was performed strictly for selection of patients,monitored the sites,shapes of occluder,whether there's any residual shunt,aortic valvular and atrioventricular valvular regurgitations and the process of the occlusion.The echocardiography data after operation was reviewed.Results: In 150 cases,118 cases got successful closure.Right position of occluder and neither residual shunt nor other complications were observed during the follow-up.Conclusions: The echocardiography is a very facilitated,reliable,repetitive follow-up mearsure with high clinical application value in the interventional treatment of ventricular septal defect.