Abstract: Objective: To observe the effects of evidence-based nursing in the emergency gastric lavage. Methods: One hundred and twenty-four patients who need emergency gastric lavage were collected and randomly divided into observation group and control group. Sixty-two patients were divided into each group. Evidence-based nursing gastric lavage was used in observation group. Traditional gastric lavage was used in control group. The time of gastric lavage,the occurrences of untoward effects and complication,the satisfaction of nursing, the score of SAS and SDS were observed. The differences of these two groups were observed. Results: The time of first liquid extraction and total gastric lavage time were significantly shorter in observation group than that in control(P < 0.01). The occurrences of untoward effects and complication were significantly lower in observation group than that in control (P < 0.01). The satisfaction of nursing, the score of SAS and SDS were significantly better in observation group than that in control (P < 0.01). Conclusions: Evidence-based nursing in the emergency gastric lavage have a shorten time of gastric lavage, low occurrence of untoward effects and complication, high satisfaction of nursing, reduce the anxiety and depressed of patients.