Abstract: Objective: To explore the clinical characteristics of angiography in patients of different ages with coronary heart disease(CHD).Methods: One hundred forty-eight CHD patients were divided into middle age-group(<60 years old),elderly group(60-74 years old) and older age-group(>74 years old).Their clinical data,biochemical indicators and coronary arteriongraphy results were compared and analyzed statistically.Results: There was less hypertension in the middle age-group than in the older age-group(P<0.05).More single-vessel lesion was found in the middle-aged,and multiple vessel diseases occurred more frequently in the elderly and the older aged(P<0.05).Right coronary artery lesions was more frequently observed in the aged than the middle-aged(P<0.05).ACC/AHA scores did not show significant statistical difference in the three groups(P>0.05).There were more diffuse lesions in the elderly group and older age-group than in the middle age-group(P<0.05).Conclusions: Coronary angiography demonstrates different characteristics for patients of different ages,and effective measures should be taken accordingly,which will be of great significance for the treatment of patients with coronary artery disease.